Wednesday, 18 February 2015

What Infertility Disorders Can Be Treated In India? | What is the cost of IVF in India

Benefits Of Getting IVF Treatments In India

Every year, thousands of patients of different health conditions and diseases flock to the country to get treatment from renowned specialists in cities like Mumbai, New Delhi, Bangalore, Hyderabad, Chennai and many others. Here are a few of the reasons why India has become one of the top destinations for IVF treatments:
• Availability of state-of-the-art technology, which cost so much more in advanced countries like the US, UK, etc.
• Use of cutting-edge techniques to treat infertility.
• Experienced IVF specialists who are just as skilled as the doctors in first world countries.
• Advanced facilities that are at par with the rest of the world to make every patient’s stay comfortable.
• Presence of English-speaking medical staff to make communication much easier compared to getting treatments in countries like Thailand or Mexico.
• Helpful medical tour consultants to help international patients find the best hospitals and most reputed medical experts in the country.

What Infertility Disorders Can Be Treated In India?

The IVF centres in India treat all types of infertility disorders to help childless patients gain the chance to get pregnant. Some of the disorders treated are as follows:
• Fallopian tubes that are blocked or damaged.
• Disorders that involve ovulation.
• Low sperm count or other disorders that are sperm-related.
• Endometriosis
Patients who do not want to spend a fortune on treatments can visit India to get world-class treatment for infertility. The doctors in the country are well-known for the personal attention that they provide to each patient and the miles they go to make sure that the treatments provided are successful.

 IVF Costs (In Vitro Fertilisation) Treatments In India:

How much does ivf treatment cost in India? Yes this is the second question comes to every patient’s mind after selecting an IVF centre. Here we have discussed a basic structure of the rates. Please note rates are subject to change as per hospitals, spread across the nation.

• Rates For Basic IVF Treatment:

For one IVF session, the average cost of treatment in India is approximately Rs. 2,50,000. This is not fixed, as it is possible that the rate can go up as high as Rs. 4,50,000 for one cycle of the treatment.

• Rates For Any Advanced Treatments:

If a patient requires advanced technological assistance in IVF, the cost can go much higher. For instance, an ICSI treatment will require an additional Rs. 1,50,000 to Rs. 2,50,000. An FET (Frozen Embryo Transfer) procedure will cost patients about Rs. 1,20,000, apart from the IVF cost in India..
If an IVF clinic promises treatment for less than Rs. 1,50,000, keep in mind that there may be additional hidden costs that will be added to a patient’s bill later. Patients should always ask if the treatment rate quoted includes expenses such as cost of fertility drugs, blood work, monitoring and ultrasound, etc. Asking well-researched questions before getting the treatment can save you from surprisingly high medical bills and disputes with the clinic.
Infertility specialists in IVF clinics in India have the ability and technology to provide satisfactory solutions for infertility. With so many reputed centres in different cities across the country, patients can increase their chances of conceiving. By this they can realize their dream of becoming happy parents of a beautiful and healthy baby!

Friday, 13 February 2015

Fertility Treatment Options : ICSI and IVF for Male Infertility, Sperm Injection Into Eggs

Intracytoplasmic sperm injection (ICSI) can be used as part of an in vitro fertilisation (IVF) treatment to help you and your spouse to conceive a child. 

ICSI is the most successful form of treatment for men who are infertile and is used in nearly half of all IVF treatments. 
ICSI only requires one sperm, which is injected directly into the egg. The fertilised egg (embryo) is then transferred to your uterus (womb).




1.     Severe male factor infertility that do not want donor sperm insemination.
2.     Couples with infertility with:
o    Sperm concentrations of less than 15-20 million per milliliter
o    Low sperm motility - less than 35%
o    Very poor sperm morphology (subjective - specific cutoff value is debatable)
3.     Having previous IVF with no fertilization - or a low rate of fertilization (low percentage of mature eggs that were normally fertilized).
4.     Sometimes it is used for couples that have a low yield of eggs at egg retrieval. In this scenario, ICSI is being used to try to get a higher percentage of eggs fertilized than with conventional insemination of the eggs (mixing eggs and sperm together).

1.     The mature egg is held with a specialized holding pipette.
2.     A very delicate, sharp and hollow needle is used to immobilize and pick up a single sperm.
3.     This needle is then carefully inserted through the zona (shell of the egg) and in to the center (cytoplasm) of the egg.
4.     The sperm is injected in the cytoplasm and the needle is removed.
5.     The eggs are checked the next morning for evidence of normal fertilization.

How long does ICSI treatment last?

One cycle of ICSI takes between four weeks and six weeks to complete. You and your spouse can expect to spend a full day at the clinic for the egg and sperm retrieval procedures. You'll go back anywhere between two days and six days later for the embryo transfer procedure.

What are the success rates of ICSI?

The success rates for ICSI are higher than if you use conventional IVF methods. A lot depends on your particular fertility problem and your age. The younger you are, the healthier your eggs usually are, and the higher your chances of success
The percentage of cycles using ICSI which result in a live birth are:

  • 35 per cent if you are under 35
  • 29 per cent if you are between 35 and 37
  • 21 per cent if you are between 38 and 39
  • 14 per cent if you are aged between 40 and 42
  • six per cent if you are between 43 and 44
  • five per cent if you are over 44



What are the advantages of ICSI?

  • ICSI may give you and your spouse a chance of conceiving your genetic child when other options are closed to you.
  • If your spouse is too anxious to ejaculate on the day of egg collection for standard IVF, sperm can instead be extracted for ICSI.
  • ICSI can also be used to help couples with unexplained infertility, though experts haven't found that ICSI makes pregnancy any more likely than standard IVF.
  • ICSI doesn't appear to affect how children conceived via the procedure develop mentally or physically
    .



Monday, 3 March 2014

IVF - Frequently Asked Questions - Male & Female Fertility Treatment in India

1. Are there any restrictions on physical or personal activities during an IVF cycle?
  • Smoking: Stop smoking before ovulation induction begins. It is best to discontinue tobacco at least 3 months prior to an IVF cycle. If you cannot stop “cold turkey”, seek the care of your primary care physician. By products of tobacco have been demonstrated to be toxic to the oocyte (egg). We strongly recommend that all women, especially those undergoing fertility treatment, cease smoking.
  • Drinking: Alcohol is a drug, and should be avoided during infertility treatment and pregnancy. Please do not drink alcohol from the time fertility medications are initiated until the pregnancy test.
  • Medications: If you are taking any medication, prescription or over-the-counter, please inform your physician. Some medications may interfere with the fertility medications prescribed, some are not safe to use before an operation or medical procedure, and others might interfere with ovulation or pregnancy implantation.
  • An IVF cycle can be an emotional and stressful time for you and your partner. It may be helpful to have supportive personnel to speak to, such as friends and family, a clergy member, or a psychologist/therapist.
  • Heavy exercise such as aerobics, jogging, weight lifting etc. are prohibited during ovarian stimulation and until the pregnancy test results are known.
  • Acupuncture is permitted prior, during and after your IVF cycle but herbal supplements are absolutely prohibited.
2. Is the egg retrieval painful?
We do our egg retrievals under anesthesia you will be asleep for the procedure. Our anesthesia specialists use medications which heavily sedate you. You will be "asleep" however; you will not require a breathing tube. The beauty of this approach is that you will feel absolutely nothing, remember absolutely nothing, and will have few of or none of the typical side effects of anesthesia such as nausea and vomiting.

3. Will the egg retrieval damage my ovaries?
The data we have available tells us that it does not. There have been many women who have undergone multiple egg retrievals. The fact that they have responded to stimulation on subsequent occasions and gotten eggs and pregnancies on these occasions implies that the ovaries are OK after egg retrieval. There have been some limited studies looking at the appearance of the ovaries in women who have had egg retrievals and subsequent laparoscopic surgery. In those patients, the findings were normal.


From the point of your initial consultation , you may potentially start an IVF cycle within weeks. Your physician will determine the appropriate time frame for your fertility treatment.

IVF treatment into phases:

Phase One involves your initial consult and diagnostic evaluation. This can take days, but usually takes weeks or even a couple of months (depending on your menstrual cycle, logistical and financial details such as your travel schedule, availability, insurance requirements, etc.)

Phase Two is your cycle planning stage, which is heavy on logistical details such as obtaining IVF medications and learning how to mix and administer them. There is also blood work to be done, consent forms to be signed, payment to be made as well as other details to attend to during this phase.

Phase Two can last days, weeks or months, depending on your schedule, insurance, and availability.

Phase Three is the start of the cycle and usually lasts about two weeks. During this time you will be taking injectable medications and return  every couple of days for monitoring.

Phase Four is egg retrieval and embryo transfer. There are three to five days between the time when eggs are retrieved and embryos are put back into the uterus.

Phase Five is a pregnancy test and beyond.

5. If I am not pregnant, when can we try again?
Usually we ask that patients wait one or two complete menstrual cycles before beginning another ART cycle. Sometimes tests are required that may delay subsequent cycles.

We find that most couples will get pregnant within 2 tries. Occasionally, there may be a reason to do a third attempt but that is not common. More than this would really require extenuating circumstances such as a miscarriage due to a non-recurring reason, for example.

7. Is there a higher miscarriage rate for ART patients?
The miscarriage rate is about the same for ART as the general population. Many times older females undergo ART and their miscarriage rates are naturally higher. Since pregnancy testing is done two weeks after embryo transfer, we often know about spontaneous miscarriages in the very early stages of pregnancy. These miscarriages would probably go unnoticed in the general population.

8. What are my choices if my tubes have been tied?
Basically there are two choices, surgery to try and repair the tubes or IVF. There are pros and cons to each choice and often the best choice depends on your unique situation. Surgery offers the option of attempting pregnancy naturally indefinitely without repeated treatments, but carries the rare risks of surgery and in some cases is not successful depending on the type of tubal ligation or tubal damage done initially. IVF offers the chance for pregnancy without having to undergo an operation and maintaining contraception or birth control against future pregnancies after completion of your family.

9. How do we decide how many embryos to transfer?
Your physician will discuss this with you at the time of consent signing, but we usually follow the recommendations of The American Society for Reproductive Medicine guidelines:
  • Under 34 years old = 1-2 embryos
  • 35-37 years of age = 2-3 embryos
  • 38-40 years of age = 3 embryos
These numbers may vary depending on individual diagnosis and clinical circumstance.


10.How much does IVF cost?
The cost of IVF depends on the treatment and options selected. For IVF pricing information, click
here.

Friday, 31 January 2014

Treatment for Low Sperm Count - ICSI (Intracytoplasmic Sperm Injection)

If there is a question of the sperm's ability to fertilize the egg, due to either a low sperm count or poor quality of the sperm, that poses no problem whatsoever. Intra-CytoplasmicSperm Injection (ICSI) would be performed instead of regular In Vitro Fertilization (IVF). With ICSI, the eggs are retrieved the same as if you were doing conventional IVF. However, the eggs and the sperm are then fertilized in the laboratory, by direct injection of a single sperm into each egg. Three days later the resulting embryos are simply placed into your uterus with no surgery, just as with IVF. Extra embryos are frozen for later attempts at pregnancy.
The availability of this Intra-Cytoplasmic Sperm Injection, "ICSI" technique (which was developed and perfected by the Brussels University and our institution in St. Louis) means that men whose sperm previously were too weak or too few to fertilize in vitro (IVF), now have no problem fertilizing their wife's eggs. The fertilization rate per egg using ICSI is about 70% despite the sperm being terrible, the fertilization rate per infertile couple is over 99% if the wife has adequate eggs, and the pregnancy rate per treatment cycle is over 50%. This is not significantly different from regular IVF with normal sperm. This technique is very cost-effective, and will give you the same high chance for getting pregnant as any couple with normal sperm.
Non-moving "dead" appearing sperm and inject it into a woman's egg, getting a normal embryo and a completely normal baby. So far, over 10,000 babies have been born with this new technique from men who were otherwise considered hopelessly sterile. The babies are physically, mentally, and genetically completely normal, no matter how poor or miserable the sperm of the father.
We can take a man who would otherwise have to resort to donor sperm, and if we can find just a few weak sperm in his otherwise sterile appearing ejaculate, it is more than enough to microsurgically inject these few sperm into his wife's eggs, fertilize them normally, and get her pregnant.
If there is absolutely no sperm in the ejaculate, we can perform a testicle biopsy, remove the few non-moving sperm that we find through a highly refined ultra micropipette, inject it into the wife's egg and still get her pregnant. Even in testicles where allegedly there is no sperm production, we can usually (but not always) find a few sperm, which is enough for successful ICSI.
About 70 percent of eggs get fertilized. Fertilization is confirmed 18-24 hours after retrieval. ICSI is a highly successful technique used to help couples who have previously failed to achieve conception with standard IVF.
Why is ICSI Done?
  • Very Low Sperm Count
  • Abnormally Shaped Sperm
  • Poor Sperm Movement
If a man does not have any sperm in his ejaculate, but he is producing sperm, they may be retrieved through testicular sperm extraction, or TESE. Sperm retrieved through TESE require the use of ICSI. ICSI is also used in cases of retrograde ejaculation, if the sperm are retrieved from the man’s urine




IVF India has complete range of services to handle any kind of infertility with the best of professionals to back the best in class technology at work.
  • In Vitro Fertilization (IVF)
  • Intra Uterine Insemination (IUI)
  • Intra Cytoplasmic Sperm Injection (ICSI)
  • Blastocyst Culture
  • Sperm Aspiration) PESA (Percutaneous Epididymal Sperm Aspiration)
  • Advanced Treatment Options like TESE (Testicular Sperm Extraction) MESA (Microsurgical Epididymal )
  • Cryopreservation
  • Laser Assisted Hatching
  • Embryo Transfer
  • Ovulation Induction
  • Egg Donation/Egg Sharing
  • Zona free Embryo Transfer
  • Semen Bank
For more information visit:          http://www.medworldindia.com        
                    
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Tuesday, 24 December 2013

Why India has High Success Rate of Surrogacy?

An IVF cycle consists of ovarian stimulation, egg collection, fertilization, embryo culture and embryo transfer. Ovarian stimulation consists of daily injection of hormones to the female partner with frequent clinical and ultrasonographic monitoring. This usually continues for 10-15 days. Egg retrieval is performed under anaesthesia through the internal route. There are no incisions or scars.The egg and sperm are either mixed (IVF) or the sperm is injected into the egg (ICSI-intracytoplasmic sperm injection).
The fertilized egg forms the embryo. The embryo is cultured in the laboratory for 2-3 days . Two-three best embryos are selected and transferred into the womb (uterus) on the second or the third day. The pregnancy test is done 14 days after the day of embryo transfer.
                                      
Listed procedures that are imposed in India makes the huge difference in the success rates than other countries


1. Ovarian Hyper stimulation: This process includes the most important two kinds of protocols for inducing the ovaries for the treatment of IVF. The protocol known as long protocol includes down regulation inside the pituitary ovary axis with the longest usage of GnRH protagonist. As per the survey conducted by the specialists have reported that the ovarian stimulation is the most successful procedure that is conducted as it provides nearly 30% of the total number of procedures. This is the most properly conducted experiments.
 2. Natural and slight IVF: IVF can be executed by a set of collection of natural chosen egg from women’s menstrual procedures without any usage of any kind of drugs. There is another type of method known as modified natural procedure of IVF. As per the survey conducted by the physicians have reported that it is the second most successful procedure that is conducted as it provides nearly 21% of the success.
 3. Preparation of egg with sperm: The discovered eggs are marked of the circumventing cells and disposed for the process of fertilization. An acute choice may be executed prior to the process of fertilization to choose the eggs with the optimal encounter of productive pregnancy. As the reports suggested by the specialists that have been reported by the surveys as it provides nearly 19% of the success of the total set of procedures that are conducted.
 4. Fertilization: An egg is allowed to incubate with a sperm at a ratio nearly 75000:1 as per the cultural media for a long duration of about 18 hours. Maximum number of cases, the egg ends up fertilizing with the sperm within that time. This process is known as fertilization. As per the reports suggested by the specialists that have reported that the fertilization process has a success rate up to a range of about 85%. This is excellent when compared to other processes as an individual. The success rates for these types of procedures have reported as very much successful. The percentages are listed above with the proper figures.


  
4500 US Dollars - Cost includes ICSI- IVF cycle All required Medical Tests & Investigations, Top IVF Specialist
Consultations, Hysteroscopy, Medicines and Consumables, Nursing care and Airport Pick & Drop.

The above cost includes the following:-
1) Detailed Fertility Evaluation Tests prior to IVF Treatment
Tests to be done for Both Husband & Wife - CBC, ESR, Blood Sugar (fasting & PP), ABO&RH, HIV 1 & 2, BT & CT, SGPT, TSH, FT3, FT4, S. Prolactin, DHEAS, Fasting Insulin, SGOT, HBsAG,
Tests to be done for Wife only - HB electrophoresis, Liver Function test and kidney function test, Thyroid profile , Serum prolectin, LH and FSH Serum AMH Lipid profile, Serum creatnine, HCV VDRL, Urine Routine, Chest X Ray, ECG
Tests to be done for Husband only - Semen Analysis, Semen Aerobic Culture
2) IVF (In Vitro Fertilisation ) and ICSI - One Cycle.

The whole procedure takes around 4-5 weeks to complete. Accommodation to stay can be arranged by us near the hospital and will about 40 US Dollars or more depending on your choice of the hotel and the afford-ability.